Gone is the rippling physique and six pack abs and in its place is an emaciated McConaughey, playing real life figure Ron Woodruff, a man stricken with AIDS and given only a month to live. Rather than giving in and merely accepting the FDA-approved drug AZT, Woodruff began taking and selling illegal, unapproved medication acquired from all over the world. The film chronicles his fight for survival and the FDA's attempts to shut down his drug-selling operation, a battle which lasted much longer than Woodruff was ever supposed to live.
Although it's tough to tell because of the annoying ET host's voice-over, the tone appears to be walking a balance between drama and comedy, in particular with the back-and-forth between McConaughey and Jared Leto, who lost more than 30lbs to play Woodruff's transvestite partner.
Directed by Jean-Marc Vallee and co-starring Jennifer Garner, Dallas Buyers Club will debut as part of the TIFF line-up then hit theaters on November 1st. We'll update this trailer with a better one soon.